12/1/2022 0 Comments Msts scoreThe objectives were to investigate the reliability and validity of the Chinese MSTS scoring system, and to evaluate functional outcomes of the surgical treatment of lower extremity sarcoma with the Chinese MSTS. Therefore, in this study we applied the Chinese version of MSTS to a cohort of patients with lower extremity sarcoma. To the best of our knowledge, the validation of the Chinese version of the MSTS scoring system has not yet been reported. It has been cross-culturally adapted in the Chinese population, yielding good reliability and construct validity. The TESS questionnaire of lower extremity was comprised of 29 questions rated on 5-point scale, including “impossible to do,” “extremely difficult,” “moderately difficult,” “a little bit difficult,” and “not at all difficult”. The TESS questionnaire is a self-administered questionnaire evaluating functional difficulties. The total score ranges from 0 to 30, with higher scores indicating better function. Each item was rated in a scale of 0 to 5. It is composed of six items, including pain, function, emotional acceptance, use of any external support, walking ability, and gait alteration. The original version was written in English and has only been translated and validated in Brazilian and Japanese population. The MSTS Rating Scale is a widely used functional instrument which was developed in 1983 and later modified by the MSTS in 1993. In this perspective, it is necessary to develop a disease-specific instrument for patients with extremity sarcoma to determine their perceived physical and mental health.Ĭurrently, several disease-specific instruments have been used to evaluate the functional outcome of patients with extremity tumors, such as Musculoskeletal Tumor Society (MSTS) rating scale and the Toronto Extremity Salvage Score (TESS). Therefore, it is very important to apply the most suitable treatment for each patient. It is noteworthy that patients with sarcoma may have a significant heterogeneity regarding individual factors, such as age, financial capacity and nature of the tumor. Other disadvantages of limb-salvage surgery include the increased risk of infections and breakages of the prosthesis. By contrast, limb-salvage surgery may result in long period of hospitalization and not optimally functioning outcome. Depending on the location and the progressive status of the sarcoma, amputation surgery may still be necessary, despite at the cost of compromised body image. Recently, with the development of adjuvant therapies in the form of radiation therapy and chemotherapy, more patients had the opportunity to undergo limb-salvage surgery. Previously, patients with extremity sarcoma were routinely treated by amputation surgery. Sarcoma is a rare type of cancer that most frequently in the long bones and soft-tissue of the extremity. Through application of the Chinese MSTS, we demonstrated that patients receiving limb-salvage surgeries may have better functional outcome and QoL than those undergoing amputation surgeries. The Chinese MSTS scoring system is a reliable and valid instrument with well-accepted psychometric properties. The factor analysis indicated a 1-factor model with acceptable goodness of fit. 23.5 ± 6.3, p = 0.005), which indicated a good discrinimant validity of the Chinese MSTS. Patients undergoing amputation surgery had remarkably lower MSTS score than patients undergoing limb-salvage surgeries (18.8 ± 5.4 vs. The test for internal consistency showed a Cronbach’s α of 0.86 for the MSTS. The ICC was 0.91 (95% confidence interval (CI) = 0.85–0.96) for the test-retest reliability and 0.90 (95% CI = 0.86–0.93) for the inter-observer analysis. The construct validity was evaluated with the factor analysis. The discriminant validity was evaluated through comparison of the MSTS score between patients undergoing amputation surgeries and those undergoing limb-salvage surgeries. The internal consistency was evaluated by Cronbach’s α, with a value >0.70 considered acceptable. The inter-observer and test-retest reliability was analyzed with intra-class correlation coefficient (ICC). The reliability of Chinese MSTS was evaluated through test-retest analysis, inter-observer analysis and internal consistency. Assessment of psychometric properties was carried out through reliability and validity test. All the patients completed the clinical assessment with the Chinese MSTS and the Chinese Toronto Extremity Salvage Score (TESS). MethodsĪ cohort of 98 patients who had undergone surgery for lower extremity sarcoma were included. This study aims to investigate the reliability and validity of the Chinese version of the MSTS, and to evaluate functional outcomes of the surgical treatment of lower extremity sarcoma using the Chinese MSTS. The Musculoskeletal Tumor Society (MSTS) scoring system is a disease-specific instrument to determine the physical and mental health for patients with extremity sarcoma.
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